[CAS NO. 80306-38-3] AR7
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PRODUCTS SPECIFICATIONS [80306-38-3]
Store
Catalog
SLK-S6605
Brand
Selleck
CAS
80306-38-3
DESCRIPTION [80306-38-3]
Overview
| MDL | MFCD27978377 |
|---|---|
| Molecular Weight | 257.71 |
| Molecular Formula | C15H12ClNO |
| SMILES | CC1=CC=C(C2=NC3=CC=C(Cl)C=C3OC2)C=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.8803 mL | 19.4017 mL | 38.8033 mL |
| 5 mM | 0.7761 mL | 3.8803 mL | 7.7607 mL |
| 10 mM | 0.3880 mL | 1.9402 mL | 3.8803 mL |
| 50 mM | - | - | - |
Description
AR7 is a antagonist.
In vitro
AR7 significantly activates CMA activity in mouse fibroblasts. A marked increase in CMA-activating potency is found when AR7 and GR1 are combined, supporting their cooperative effect. Treatment with the transcriptional repressor Actinomycin D partially reduces the stimulatory effect of AR7 on CMA, consistent with transcriptional changes contributing to the upregulation of CMA.
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