[CAS NO. 1416799-28-4]  AMG-333

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PRODUCTS SPECIFICATIONS [1416799-28-4]

Store
Catalog
SLK-S6638
Brand
Selleck
CAS
1416799-28-4

DESCRIPTION [1416799-28-4]

Overview

MDLMFCD31813692
Molecular Weight453.32
Molecular FormulaC20H12F5N3O4
SMILESO=C(C1=CC=C(C(N[C@H](C2=NC=CC=C2F)C3=CC=C(OC(F)(F)F)C(F)=C3)=O)N=C1)O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2059 mL11.0297 mL22.0595 mL
5 mM0.4412 mL2.2059 mL4.4119 mL
10 mM0.2206 mL1.1030 mL2.2059 mL
50 mM0.0441 mL0.2206 mL0.4412 mL

Description

AMG-333 is a potent and highly selective antagonist of with IC50 values of 13 nM and 30 nM for human TRPM8 and rat TRPM8.

Targets

human TRPM8 [1]rat TRPM8 [1]
13 nM30 nM