[CAS NO. 1369489-71-3] E7046 (ER-886406)

Name: E7046 (ER-886406)
Brand: Arctom Scientific
SKU: SLK-S6649

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PRODUCTS SPECIFICATIONS [1369489-71-3]

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Catalog

SLK-S6649

Brand

Selleck

CAS

1369489-71-3

MDL	MFCD30502665
Molecular Weight	483.39
Molecular Formula	C22H18F5N3O4
SMILES	O=C(C1C=CC([C@H](C)NC(=O)C2C(C(F)F)=NN(C)C=2OC2C=C(C(F)(F)F)C=CC=2)=CC=1)O

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

E7046 (ER-886406, Palupiprant, AN0025) is a selective inhibitor of the with IC50 of 13.5 nM and Ki of 23.14 nM.

EP4 ^[1] (Cell-free assay)	EP4 ^[1] (Cell-free assay)
13.5nM	23.14 nM(Ki)

E7046 has specific and potent inhibitory activity on PGE-mediated pro-tumor myeloid cell differentiation and activation.