[CAS NO. 2055397-18-5] WM-8014
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PRODUCTS SPECIFICATIONS [2055397-18-5]
Store
Catalog
SLK-S6655
Brand
Selleck
CAS
2055397-18-5
DESCRIPTION [2055397-18-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 384.42 |
| Molecular Formula | C20H17FN2O3S |
| SMILES | O=C(C1=CC(C2=CC=CC=C2)=CC(C)=C1F)NNS(=O)(C3=CC=CC=C3)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.6013 mL | 13.0066 mL | 26.0132 mL |
| 5 mM | 0.5203 mL | 2.6013 mL | 5.2026 mL |
| 10 mM | 0.2601 mL | 1.3007 mL | 2.6013 mL |
| 50 mM | 0.0520 mL | 0.2601 mL | 0.5203 mL |
Description
WM-8014 is a highly potent inhibitor of with an IC50 of 8 nM.
Targets
| KAT6A [1] (Cell-free assay) |
| 8 nM |
In vitro
WM-8014 induces cell cycle arrest in embryonic day (E)14.5 mouse embryonic fibroblasts.Cells treated with WM-8014 failed to proliferate after ten days of treatment (IC50 2.4 μM). Higher doses of WM-8014 (up to 40 μM) did not accelerate growth arrest, which after eight days of treatment was irreversible.
References
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