[CAS NO. 920509-32-6] Resmetirom (MGL-3196)
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PRODUCTS SPECIFICATIONS [920509-32-6]
Store
Catalog
SLK-S6663
Brand
Selleck
CAS
920509-32-6
DESCRIPTION [920509-32-6]
Overview
| MDL | MFCD26142653 |
|---|---|
| Molecular Weight | 435.22 |
| Molecular Formula | C17H12Cl2N6O4 |
| SMILES | N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.2977 mL | 11.4884 mL | 22.9769 mL |
| 5 mM | 0.4595 mL | 2.2977 mL | 4.5954 mL |
| 10 mM | 0.2298 mL | 1.1488 mL | 2.2977 mL |
| 50 mM | 0.0460 mL | 0.2298 mL | 0.4595 mL |
Description
Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective agonist with an EC50 of 0.21 μM,shows 28-fold selective for THR-β over THR-α in a functional assay.
Targets
| THR-β [1] (Cell-free assay) |
| 0.21μM(EC50) |
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