[CAS NO. 60940-34-3] Ebselen
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PRODUCTS SPECIFICATIONS [60940-34-3]
Store
Catalog
SLK-S6676
Brand
Selleck
CAS
60940-34-3
DESCRIPTION [60940-34-3]
Overview
| MDL | MFCD00210937 |
|---|---|
| Molecular Weight | 274.18 |
| Molecular Formula | C13H9NOSe |
| SMILES | O=C1N([Se]C=2C1=CC=CC2)C3=CC=CC=C3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.6472 mL | 18.2362 mL | 36.4724 mL |
| 5 mM | 0.7294 mL | 3.6472 mL | 7.2945 mL |
| 10 mM | 0.3647 mL | 1.8236 mL | 3.6472 mL |
| 50 mM | 0.0729 mL | 0.3647 mL | 0.7294 mL |
Description
Ebselen (DR 3305, SPI-1005, PZ-51, CCG-39161) is a small-molecule capsid inhibitor of Replication with IC50 of 46.1 nM in TR-FRET assay.
Targets
| HIV-1 [1] (Cell-free assay) |
| 46.1 nM |
In vitro
Ebselen acts on the early postentry step of the HIV-1 viral cycle prior to reverse transcription by stabilizing the incoming viral capsid.
Synonyms
1,2-Benzisoselenazol-3(2H)-one, 2-phenyl-
2-Phenyl-1,2-benzisoselenazol-3(2H)-one
PZ 51
Ebselen
2-Phenyl-1,2-benzoisoselenazol-3(2H)-one
NSC 639762
Lopac E 3520
CCG-39161
DR 3305
SPI 1005
2-Phenyl-1,2-benzoselenazol-3-one
2-Phenylbenzo[d][1,2]selenazol-3(2H)-one
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