[CAS NO. 415903-37-6] Grapiprant (CJ-023,423)

Name: Grapiprant (CJ-023,423)
Brand: Arctom Scientific
SKU: SLK-S6694

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PRODUCTS SPECIFICATIONS [415903-37-6]

Store

Catalog

SLK-S6694

Brand

Selleck

CAS

415903-37-6

DESCRIPTION [415903-37-6]

Overview

MDL	MFCD16628076
Molecular Weight	491.61
Molecular Formula	C26H29N5O3S
SMILES	C(C)C=1N(C=2C(N1)=C(C)N=C(C)C2)C3=CC=C(CCNC(NS(=O)(=O)C4=CC=C(C)C=C4)=O)C=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Grapiprant (CJ-023,423, AT-001, AAT-007, RQ-00000007, CJ-23423) is a novel selective inhibitor with Ki of 20 nM and 13 nM for rat EP4 receptor and human EP4 receptor, respectively.

Targets

human EP4 receptor ^[1]	rat EP4 receptor ^[1]	EP4 ^[1] (Cell-free assay)	EP4 ^[1] (Cell-free assay)
13 nM(Ki)	20 nM(Ki)	24 nM(Ki)	35 nM

References

[1] A Nagahisa, et al. J Vet Pharmacol Ther . 2017 Jun;40(3):285-292.

Synonyms

Benzenesulfonamide, N-[[[2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methyl-

N-[[[2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methylbenzenesulfonamide

2-Ethyl-4,6-dimethyl-1-[4-[2-[[[[(4-methylphenyl)sulfonyl]amino]carbonyl]amino]ethyl]phenyl]-1H-imidazo[4,5-c]pyridine

CJ 023423

AAT 007

RQ 00000007

Grapiprant

RQ 7

MR 10A7

1-[2-[4-(2-Ethyl-4,6-dimethylimidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]-3-(4-methylphenyl)sulfonylurea

Galliprant