[CAS NO. 224177-60-0]  Siramesine HCl

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PRODUCTS SPECIFICATIONS [224177-60-0]

Store
Catalog
SLK-S6756
Brand
Selleck
CAS
224177-60-0

DESCRIPTION [224177-60-0]

Overview

MDLMFCD28144522
Molecular Weight491.05
Molecular FormulaC30H32ClFN2O
SMILESFC1=CC=C(N2C=C(CCCCN3CCC4(CC3)OCC5=C4C=CC=C5)C6=C2C=CC=C6)C=C1.[H]Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.0365 mL10.1823 mL20.3645 mL
5 mM0.4073 mL2.0365 mL4.0729 mL
10 mM0.2036 mL1.0182 mL2.0365 mL
50 mM0.0407 mL0.2036 mL0.4073 mL

Description

Siramesine (Lu 28-179) is a agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively.

Targets

σ2R [1]σ1R [1]
0.12 nM17 nM