[CAS NO. 1190221-43-2] TM5441
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PRODUCTS SPECIFICATIONS [1190221-43-2]
Store
Catalog
SLK-S6778
Brand
Selleck
CAS
1190221-43-2
DESCRIPTION [1190221-43-2]
Overview
| MDL | MFCD31382187 |
|---|---|
| Molecular Weight | 428.82 |
| Molecular Formula | C21H17ClN2O6 |
| SMILES | O=C(O)C1=CC(Cl)=CC=C1NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.3320 mL | 11.6599 mL | 23.3198 mL |
| 5 mM | 0.4664 mL | 2.3320 mL | 4.6640 mL |
| 10 mM | 0.2332 mL | 1.1660 mL | 2.3320 mL |
| 50 mM | 0.0466 mL | 0.2332 mL | 0.4664 mL |
Description
TM5441 is an orally bioavailable inhibitor of with IC50 ranging between 9.7 μM and 60.3 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines.
Targets
| PAI-1 [1] (Cell-free assay) |
| 9.7 μM |
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