Overview
| MDL | MFCD32174287 |
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| Molecular Weight | 388.19 |
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| Molecular Formula | C17H11BrFN3O2 |
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| SMILES | O=C(C1=CC(C(C2=C(F)C=CC=C2Br)=O)=CN1)NC3=CC=CN=C3 |
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For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg |
| 1 mM | 2.5761 mL | 12.8803 mL | 25.7606 mL |
| 5 mM | 0.5152 mL | 2.5761 mL | 5.1521 mL |
| 10 mM | 0.2576 mL | 1.2880 mL | 2.5761 mL |
| 50 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL |
Description
ERK5-IN-2 is an orally active, sub-micromolar, selective inhibitor with IC50 of 0.82 μM and 3 μM for ERK5 and ERK5 MEF2D, respectively.
Targets
ERK5 [1] (Cell-free assay) | ERK5 MEF2D [1] (Cell-free assay) |
| 0.82 μM | 3 μM |