[CAS NO. 457081-03-7]  JAK Inhibitor I (Pyridone 6)

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PRODUCTS SPECIFICATIONS [457081-03-7]

Store
Catalog
SLK-S6789
Brand
Selleck
CAS
457081-03-7

DESCRIPTION [457081-03-7]

Overview

MDLMFCD06411425
Molecular Weight309.34
Molecular FormulaC18H16FN3O
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.2327 mL16.1634 mL32.3269 mL
5 mM0.6465 mL3.2327 mL6.4654 mL
10 mM0.3233 mL1.6163 mL3.2327 mL
50 mM0.0647 mL0.3233 mL0.6465 mL

Description

JAK Inhibitor I (Pyridone 6, CMP 6, Compound 6) is a pan-JAK inhibitor with IC50s of 1 nM, 1 nM, 5 nM and 15 nM for , , and , respectively.

Targets

JAK2 [1]TYK2 [1]JAK3 [1]
1 nM1 nM5 nM