[CAS NO. 892711-75-0]  CDN1163

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PRODUCTS SPECIFICATIONS [892711-75-0]

Store
Catalog
SLK-S6815
Brand
Selleck
CAS
892711-75-0

DESCRIPTION [892711-75-0]

Overview

MDL-
Molecular Weight320.39
Molecular FormulaC20H20N2O2
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.1212 mL15.6060 mL31.2120 mL
5 mM0.6242 mL3.1212 mL6.2424 mL
10 mM0.3121 mL1.5606 mL3.1212 mL
50 mM0.0624 mL0.3121 mL0.6242 mL

Description

CDN1163 is a small molecular allosteric activator of the that improves Ca2+ homeostasis.

Targets

SERCA [1]

In vitro

CDN1163 treatment significantly reduces the hepatic expression of genes involved in gluconeogenesis and lipogenesis, attenuates ER stress response and ER stress-induced apoptosis, and improves mitochondrial biogenesis, possibly through SERCA2-mediated activation of AMP-activated protein kinase pathway.