[CAS NO. 66-71-7] o-Phenanthroline
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PRODUCTS SPECIFICATIONS [66-71-7]
Store
Catalog
SLK-S6830
Brand
Selleck
CAS
66-71-7
DESCRIPTION [66-71-7]
Overview
| MDL | MFCD00011678 |
|---|---|
| Molecular Weight | 180.21 |
| Molecular Formula | C12H8N2 |
| SMILES | C12=C3C(=CC=C1C=CC=N2)C=CC=N3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 5.5491 mL | 27.7454 mL | 55.4908 mL |
| 5 mM | 1.1098 mL | 5.5491 mL | 11.0982 mL |
| 10 mM | 0.5549 mL | 2.7745 mL | 5.5491 mL |
| 50 mM | 0.1110 mL | 0.5549 mL | 1.1098 mL |
Description
o-Phenanthroline (1,10-Phenanthroline, phen), a hypoxia-mimicking agent, is a non-specific inhibitor with IC50 of 110.5μM for . O-phenanthroline reduces the expression of and mRNA levels during chondrogenic differentiation of human chondrocytes (hChs), as well as after TNFα/IL-1β exposure in an explant model. o-Phenanthroline is also a chelator which prevents the induction of chromosomal aberrations in streptozotocin-treated cells and forms a red chelate with that absorbs maximally at 510 nm.
References
Synonyms
1,10-Phenanthroline
4,5-Diazaphenanthrene
o-Phenanthroline
β-Phenanthroline
1,10-o-Phenanthroline
Activ-8
TS 20
TS 20 (amine)
NSC 203545
11,10-Phenanthroline
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