[CAS NO. 1713240-67-5]  CM 4620

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PRODUCTS SPECIFICATIONS [1713240-67-5]

Store
Catalog
SLK-S6834
Brand
Selleck
CAS
1713240-67-5

DESCRIPTION [1713240-67-5]

Overview

MDL-
Molecular Weight421.76
Molecular FormulaC19H11ClF3N3O3
SMILESO=C(NC1=NC=C(C2=C(Cl)C=C(OC(F)(F)O3)C3=C2)N=C1)C4=C(C)C=CC=C4F

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3710 mL11.8551 mL23.7102 mL
5 mM0.4742 mL2.3710 mL4.7420 mL
10 mM0.2371 mL1.1855 mL2.3710 mL
50 mM0.0474 mL0.2371 mL0.4742 mL

Description

CM 4620 is an inhibitor of . CM4620 inhibits Orai1/STIM1-mediated Ca2+ currents and Orai2/STIM1-mediated currents with IC50 of near 120 nM and 900 nM, respectively.

Targets

Orai1/STIM1-mediated Ca2+ currents [1]
(Cell-free assay)
Orai2/STIM1-mediated currents [1]
(Cell-free assay)
120 nM900 nM

In vitro

CM4620 inhibits Orai1/STIM1-mediated Ca2+ currents and Orai2/STIM1-mediated currents with IC50 of near 120 nM and 900 nM, respectively.