[CAS NO. 393514-24-4]  BCTC

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PRODUCTS SPECIFICATIONS [393514-24-4]

Store
Catalog
SLK-S6838
Brand
Selleck
CAS
393514-24-4

DESCRIPTION [393514-24-4]

Overview

MDLMFCD08690556
Molecular Weight372.89
Molecular FormulaC20H25ClN4O
SMILESClC1=C(N2CCN(C(NC3=CC=C(C(C)(C)C)C=C3)=O)CC2)N=CC=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.6818 mL13.4088 mL26.8176 mL
5 mM0.5364 mL2.6818 mL5.3635 mL
10 mM0.2682 mL1.3409 mL2.6818 mL
50 mM0.0536 mL0.2682 mL0.5364 mL

Description

BCTC is an orally effective and highly potent antagonist. BCTC inhibits capsaicin-induced and acid-induced activation of rat VR1 with IC50 of 35 nM and 6.0 nM, respectivley. BCTC exhibits anti-tumor activity.

Targets

rTRPV1 (acid-induced) [1]
(Cell-free assay)
rTRPV1 (capsaicin-induced) [1]
(Cell-free assay)
6.0 nM35 nM