[CAS NO. 2130958-55-1] Alflutinib (AST2818) mesylate
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PRODUCTS SPECIFICATIONS [2130958-55-1]
Store
Catalog
SLK-S6868
Brand
Selleck
CAS
2130958-55-1
DESCRIPTION [2130958-55-1]
Overview
| MDL | MFCD31746903 |
|---|---|
| Molecular Weight | 664.7 |
| Molecular Formula | C29H35F3N8O5S |
| SMILES | CN1C2=CC=CC=C2C(C3=NC(NC4=C(OCC(F)(F)F)N=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3)=C1.OS(=O)(C)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.5044 mL | 7.5222 mL | 15.0444 mL |
| 5 mM | 0.3009 mL | 1.5044 mL | 3.0089 mL |
| 10 mM | 0.1504 mL | 0.7522 mL | 1.5044 mL |
| 50 mM | - | - | - |
Description
Alflutinib (AST2818, Furmonertinib) mesylate is a third-generation inhibitor that inhibits both EGFR-sensitive mutations and T790M mutations. Alflutinib (AST2818), primarily metabolized by CYP3A4, is also a potent inducer with EC50 of 0.25 μM.
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