[CAS NO. 925432-73-1] SRT-1460

Name: SRT-1460
Brand: Arctom Scientific
SKU: SLK-S6880

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PRODUCTS SPECIFICATIONS [925432-73-1]

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Catalog

SLK-S6880

Brand

Selleck

CAS

925432-73-1

DESCRIPTION [925432-73-1]

Overview

MDL	MFCD19053214
Molecular Weight	507.60
Molecular Formula	C26H29N5O4S
SMILES	C(C=1N2C(=NC(=C2)C3=C(NC(=O)C4=CC(OC)=C(OC)C(OC)=C4)C=CC=C3)SC1)N5CCNCC5

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.9701 mL	9.8503 mL	19.7006 mL
5 mM	0.3940 mL	1.9701 mL	3.9401 mL
10 mM	0.1970 mL	0.9850 mL	1.9701 mL
50 mM	-	-	-

Description

SRT-1460 is a potent and selective activator of with EC1.5 of 2.9 μM. SRT-1460 reduces cell viability and growth of pancreatic cancer cells and induces .

Targets

SIRT1 ^[1]
(Cell-free assay)

2.9 μM(EC1.5)

References

[1] Jill C Milne, et al. Nature. 2007 Nov 29;450(7170):712-6.
[2] Claudia C S Chini, et al. Clin Cancer Res. 2016 May 15;22(10):2496-507.

Synonyms

Benzamide, 3,4,5-trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-

3,4,5-Trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]benzamide

3,4,5-Trimethoxy-N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]benzamide