[CAS NO. 2260886-64-2]  JND3229

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PRODUCTS SPECIFICATIONS [2260886-64-2]

Store
Catalog
SLK-S6881
Brand
Selleck
CAS
2260886-64-2

DESCRIPTION [2260886-64-2]

Overview

MDL-
Molecular Weight617.18
Molecular FormulaC33H41ClN8O2
SMILESCCC(N[C@H]1CC[C@@H](CC1)N(C2=O)C3=NC(NC4=CC=C(C(C)=C4)N5CCN(CC5)C)=NC=C3CN2C6=CC=CC=C6Cl)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.6203 mL8.1014 mL16.2027 mL
5 mM0.3241 mL1.6203 mL3.2405 mL
10 mM0.1620 mL0.8101 mL1.6203 mL
50 mM0.0324 mL0.1620 mL0.3241 mL

Description

JND3229 is a potent reversible inhibitor of with an IC50 value of 5.8 nM. JND3229 also potently suppresses and with IC50 values of 30.5 nM and 6.8 nM, respectively.

Targets

EGFR C797S [1]EGFR WT [1]EGFR L858R/T790M [1]
5.8 nM6.8 nM30.5 nM