[CAS NO. 465-16-7] Oleandrin (PBI-05204)

Name: Oleandrin (PBI-05204)
Brand: Arctom Scientific
SKU: SLK-S6918

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PRODUCTS SPECIFICATIONS [465-16-7]

Store

Catalog

SLK-S6918

Brand

Selleck

CAS

465-16-7

DESCRIPTION [465-16-7]

Overview

MDL	MFCD00079204
Molecular Weight	576.72
Molecular Formula	C32H48O9
SMILES	O[C@@]12[C@@](C)([C@]([C@@H](OC(C)=O)C1)(C3=CC(=O)OC3)[H])CC[C@]4([C@]2(CC[C@]5([C@]4(C)CC[C@H](O[C@H]6C[C@H](OC)[C@@H](O)[C@H](C)O6)C5)[H])[H])[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.7339 mL	8.6697 mL	17.3394 mL
5 mM	0.3468 mL	1.7339 mL	3.4679 mL
10 mM	0.1734 mL	0.8670 mL	1.7339 mL
50 mM	0.0347 mL	0.1734 mL	0.3468 mL

Description

Oleandrin (PBI-05204, Foliandrin, Neriolin, Neriostene, Folinerin, Corrigen, Neriol) is an inhibitor of with IC50 of 0.62 μM. Oleandrin induces and reduces migration of human glioma cells in vitro.

Targets

Na+/K+-ATPase ^[1]
(Cell-free assay)

0.62 μM

References

[1] S A Jortani, et al. Clin Chem. 1996 Oct;42(10):1654-8.
[2] Stefano Garofalo, et al. J Neurosci. 2017 Apr 5;37(14):3926-3939.

Synonyms

Card-20(22)-enolide, 16-(acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-14-hydroxy-, (3β,5β,16β)-

Oleandrin

(3β,5β,16β)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide

Corrigen

Foliandrin

Folinerin

Oleandrine

Neriol

Neriostene

Neriolin

Oleandrigenin 3-O-α-L-oleandroside