[CAS NO. 1062271-24-2]  MK6-83

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PRODUCTS SPECIFICATIONS [1062271-24-2]

Store
Catalog
SLK-S6947
Brand
Selleck
CAS
1062271-24-2

DESCRIPTION [1062271-24-2]

Overview

MDL-
Molecular Weight336.47
Molecular FormulaC16H20N2O2S2
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9720 mL14.8602 mL29.7203 mL
5 mM0.5944 mL2.9720 mL5.9441 mL
10 mM0.2972 mL1.4860 mL2.9720 mL
50 mM0.0594 mL0.2972 mL0.5944 mL

Description

MK6-83 is a novel activator that may be used as a potential pharmacological treatment option for a specific subgroup of MLIV patients.

Targets

TRPML1 [1]

In vitro

MK6-83 activates MCOLN1 and triggers cell death of a number of cancer cells by evoking autophagic arrest and subsequent apoptotic response and cell cycle arrest, with little or no effect observed on normal cells.