[CAS NO. 2060530-16-5] K-Ras(G12C) inhibitor 6
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PRODUCTS SPECIFICATIONS [2060530-16-5]
Store
Catalog
SLK-S7333
Brand
Selleck
CAS
2060530-16-5
DESCRIPTION [2060530-16-5]
Overview
| MDL | MFCD28099807 |
|---|---|
| Molecular Weight | 405.34 |
| Molecular Formula | C17H22Cl2N2O3S |
| SMILES | C(COC1=C(Cl)C=C(Cl)C=C1)(=O)N2CCC(NC(CCCS)=O)CC2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
K-Ras(G12C) inhibitor 6 is an allosteric, and selective inhibitor of oncogenic .
Features
Allosteric, K-Ras(G12C)-selective inhibitor.
Targets
| K-Ras(G12C) [1] (Cell-free assay) |
In vitro
K-Ras(G12C) inhibitor 6 belongs to a series of small molecules, which irreversibly bind to a common oncogenic mutant K-Ras(G12C) and blocks K-Ras(G12C) interactions. Some of them decrease viability and increase apoptosis of G12C-containing cancer cell lines.
Synonyms
Butanamide, N-[1-[2-(2,4-dichlorophenoxy)acetyl]-4-piperidinyl]-4-mercapto-
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