Overview
| MDL | MFCD26936345 |
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| Molecular Weight | 338.24 |
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| Molecular Formula | C15H20BrN3O |
|---|
| SMILES | O=C(C1=CC(Br)=CN=C1)N2CCC(N3CCCC3)CC2 |
|---|
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg |
| 1 mM | 2.9565 mL | 14.7824 mL | 29.5648 mL |
| 5 mM | 0.5913 mL | 2.9565 mL | 5.9130 mL |
| 10 mM | 0.2956 mL | 1.4782 mL | 2.9565 mL |
| 50 mM | 0.0591 mL | 0.2956 mL | 0.5913 mL |
Description
UNC669 is a potent and selective (malignant brain tumor) inhibitor with of 6 μM for , 5- and 11-fold selective over L3MBTL3 and L3MBTL4.
Features
MBT-selective chemical probe.
Targets
| L3MBTL1 [1] | L3MBTL3 [1] | L3MBTL4 [1] |
| 6 μM | 35 μM | 69 μM |
In vitro
UNC669, as a low μM binder of L3MBTL1, provides new directions for optimization of MBT inhibitors to improve potency and selectivity.