[CAS NO. 88191-84-8]  MDL-28170

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PRODUCTS SPECIFICATIONS [88191-84-8]

Store
Catalog
SLK-S7394
Brand
Selleck
CAS
88191-84-8

DESCRIPTION [88191-84-8]

Overview

MDLMFCD28137700
Molecular Weight382.45
Molecular FormulaC22H26N2O4
SMILESC(C(NC([C@@H](NC(OCC1=CC=CC=C1)=O)[C@H](C)C)=O)C=O)C2=CC=CC=C2

For research use only.

Storage

2 years -80 in solvent
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.6147 mL13.0736 mL26.1472 mL
5 mM0.5229 mL2.6147 mL5.2294 mL
10 mM0.2615 mL1.3074 mL2.6147 mL
50 mM0.0523 mL0.2615 mL0.5229 mL

Description

MDL-28170 (Calpain Inhibitor III) is a potent and selective inhibitor of calpain that penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration. MDL-28170 is also an inhibitor of .

Targets

calpain [1]Secretase [2]

In vitro

MDL28170 significantly enhances Schwann cells (SCs) survival in vitro in response to oxidative stress induced by application of HO, without reducing LDH release.


Synonyms

Carbamic acid, N-[(1S)-1-[[(1-formyl-2-phenylethyl)amino]carbonyl]-2-methylpropyl]-, phenylmethyl ester
Carbamic acid, [(1S)-1-[[(1-formyl-2-phenylethyl)amino]carbonyl]-2-methylpropyl]-, phenylmethyl ester
Phenylmethyl N-[(1S)-1-[[(1-formyl-2-phenylethyl)amino]carbonyl]-2-methylpropyl]carbamate
MDL 28170
Calpain Inhibitor III
Calp III