[CAS NO. 1421227-52-2]  WS3

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PRODUCTS SPECIFICATIONS [1421227-52-2]

Store
Catalog
SLK-S7441
Brand
Selleck
CAS
1421227-52-2

DESCRIPTION [1421227-52-2]

Overview

MDLMFCD26142950
Molecular Weight569.58
Molecular FormulaC28H30F3N7O3
SMILESO=C(C1CC1)NC2=NC=NC(OC3=CC=C(NC(NC4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4)=O)C=C3)=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.7557 mL8.7784 mL17.5568 mL
5 mM0.3511 mL1.7557 mL3.5114 mL
10 mM0.1756 mL0.8778 mL1.7557 mL
50 mM0.0351 mL0.1756 mL0.3511 mL

Description

WS3 is a β cell proliferation inducer via modulation of and the pathway.

Targets

EBP1 [1]IκB kinase [1]

In vitro

WS3 induces proliferation of the mouse β cell line R7T1 with EC50 of 0.074 μM. WS3 reversibly induces proliferation of primary fetal and adult human retinal pigment epithelial (RPE) cells.