[CAS NO. 219793-45-0] BTB06584
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PRODUCTS SPECIFICATIONS [219793-45-0]
Store
Catalog
SLK-S7460
Brand
Selleck
CAS
219793-45-0
DESCRIPTION [219793-45-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 417.82 |
| Molecular Formula | C19H12ClNO6S |
| SMILES | ClC1=CC=C(C(OC2=C([N+]([O-])=O)C=CC(S(C3=CC=CC=C3)(=O)=O)=C2)=O)C=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial .
Targets
| F1 Fo-ATPase [1] |
In vitro
BTB06584 IF1-dependently inhibits F1 Fo-ATPase activity with no effect on without compromising ATP synthesis, and also limits ischemia-induced injury caused by reversal of the mitochondrial F1 Fo-ATP synthase.
In vivo
BTB06584 rescues the defective haemoglobin synthesis in zebrafish pinotage (pnt) mutants without causing significant toxicity.
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