[CAS NO. 1243583-85-8] MG149
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PRODUCTS SPECIFICATIONS [1243583-85-8]
Store
Catalog
SLK-S7476
Brand
Selleck
CAS
1243583-85-8
DESCRIPTION [1243583-85-8]
Overview
| MDL | MFCD22123243 |
|---|---|
| Molecular Weight | 340.46 |
| Molecular Formula | C22H28O3 |
| SMILES | O=C(O)C1=C(O)C=CC=C1CCC2=CC=C(CCCCCCC)C=C2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9372 mL | 14.6860 mL | 29.3720 mL |
| 5 mM | 0.5874 mL | 2.9372 mL | 5.8744 mL |
| 10 mM | 0.2937 mL | 1.4686 mL | 2.9372 mL |
| 50 mM | 0.0587 mL | 0.2937 mL | 0.5874 mL |
Description
MG149 (Tip60 HAT inhibitor) is a potent inhibitor with of 74 μM and 47 μM for Tip60 and MOF,respectively.
In vitro
MG149 targets the acetyl-CoA binding site, and inhibits acetyltransferase activity of nuclear extract from tissue samples from different brain regions in mice. MG149 also inhibits the p53 and the NF-κB pathways.
References
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