[CAS NO. 865759-25-7] Trelagliptin

Name: Trelagliptin
Brand: Arctom Scientific
SKU: SLK-S7513

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [865759-25-7]

Store

Catalog

SLK-S7513

Brand

Selleck

CAS

865759-25-7

DESCRIPTION [865759-25-7]

Overview

MDL	MFCD22572746
Molecular Weight	357.38
Molecular Formula	C18H20FN5O2
SMILES	C(N1C(=CC(=O)N(C)C1=O)N2C[C@H](N)CCC2)C3=C(C#N)C=CC(F)=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.7981 mL	13.9907 mL	27.9814 mL
5 mM	0.5596 mL	2.7981 mL	5.5963 mL
10 mM	0.2798 mL	1.3991 mL	2.7981 mL
50 mM	0.0560 mL	0.2798 mL	0.5596 mL

Description

Trelagliptin (SYR-472), a potent, orally active and highly selective inhibitor with an IC50 of 4 nM, improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM).

Targets

DPP-4 ^[1]

4 nM

References

[1] Patel BD, et al. Eur J Med Chem. 2014 Mar 3;74:574-605.

Synonyms

Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluoro-

2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile

Trelagliptin

(R)-2-[[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl]-4-fluorobenzonitrile

(R)-2-[[6-(3-AMinopiperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl]Methyl]-4-fluorobenzonitrile

2-[[6-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile