[CAS NO. 1416133-89-5]  JW642

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PRODUCTS SPECIFICATIONS [1416133-89-5]

Store
Catalog
SLK-S7543
Brand
Selleck
CAS
1416133-89-5

DESCRIPTION [1416133-89-5]

Overview

MDLMFCD22987956
Molecular Weight462.39
Molecular FormulaC21H20F6N2O3
SMILESO=C(N1CCN(CC2=CC=CC(OC3=CC=CC=C3)=C2)CC1)OC(C(F)(F)F)C(F)(F)F

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.1627 mL10.8134 mL21.6268 mL
5 mM0.4325 mL2.1627 mL4.3254 mL
10 mM0.2163 mL1.0813 mL2.1627 mL
50 mM0.0433 mL0.2163 mL0.4325 mL

Description

JW642 is a potent inhibitor of that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.

Targets

human MAGL [1]mouse MAGL [1]rat MAGL [1]
3.7 nM7.6 nM14 nM