[CAS NO. 1453848-26-4]  Ravoxertinib (GDC-0994)

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PRODUCTS SPECIFICATIONS [1453848-26-4]

Store
Catalog
SLK-S7554
Brand
Selleck
CAS
1453848-26-4

DESCRIPTION [1453848-26-4]

Overview

MDLMFCD28143918
Molecular Weight439.85
Molecular FormulaC21H18ClFN6O2
SMILESO=C1C=C(C2=NC(NC3=CC=NN3C)=NC=C2)C=CN1[C@@H](C4=CC=C(Cl)C(F)=C4)CO

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Ravoxertinib (GDC-0994) is a potent, orally available and highly selective inhibitor with of 1.1 nM and 0.3 nM, respectively. Phase 1.

Targets

ERK2 [1]
(Cell-free assay)
ERK1 [1]
(Cell-free assay)
0.3 nM1.1 nM

In vitro

GDC-0994 potently inhibits phospho-p90RSK in tumor cells.