[CAS NO. 879487-87-3] R-268712

Name: R-268712
Brand: Arctom Scientific
SKU: SLK-S7710

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PRODUCTS SPECIFICATIONS [879487-87-3]

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Catalog

SLK-S7710

Brand

Selleck

CAS

879487-87-3

MDL	MFCD28963939
Molecular Weight	363.39
Molecular Formula	C20H18FN5O
SMILES	CC1=NC(C=2C(=CNN2)C3=CC(=C(F)C=C3)C4=CN(CCO)N=C4)=CC=C1

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

R-268712 is a potent and selective inhibitor of with an IC50 of 2.5 nM.

ALK5 ^[1]
(in ALK5 kinase activity assay)

2.5 nM

1H-Pyrazole-1-ethanol, 4-[2-fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-

4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol

2-[4-[2-Fluoro-5-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazol-1-yl]ethanol

R 268712

2-[4-[2-Fluoro-5-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol