[CAS NO. 1018899-04-1]  Sotagliflozin (LX4211)

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PRODUCTS SPECIFICATIONS [1018899-04-1]

Store
Catalog
SLK-S8103
Brand
Selleck
CAS
1018899-04-1

DESCRIPTION [1018899-04-1]

Overview

MDLMFCD22493506
Molecular Weight424.94
Molecular FormulaC21H25ClO5S
SMILESO[C@H]1[C@@H](O[C@H](SC)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3533 mL11.7664 mL23.5327 mL
5 mM0.4707 mL2.3533 mL4.7065 mL
10 mM0.2353 mL1.1766 mL2.3533 mL
50 mM0.0471 mL0.2353 mL0.4707 mL

Description

Sotagliflozin (LX4211, LP-802034) is an oral dual inhibitor with of 36 nM and 1.8 nM, respectively. Phase 3.

Targets

SGLT2 [1]SGLT1 [1]
1.8 nM36 nM

In vitro

LX4211 inhibits [C]AMG uptake with IC50 of 62.0 nM for mouse SGLT1 and 0.6 nM for mouse SGLT2, respectively.


Synonyms

β-L-Xylopyranoside, methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-, (5S)-
(5S)-Methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-β-L-xylopyranoside
Sotagliflozin
LP 802034
LX 4211
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