APTSTAT3-9R
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS
Store
Catalog
SLK-S8197
Brand
Selleck
CAS
-
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 4947.51 |
| Molecular Formula | C223H330N80O51 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.2021 mL | 1.0106 mL | 2.0212 mL |
| 5 mM | 0.0404 mL | 0.2021 mL | 0.4042 mL |
| 10 mM | 0.0202 mL | 0.1011 mL | 0.2021 mL |
| 50 mM | - | - | - |
Description
APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating motif. The treatment of APTSTAT3-9R in various types of cancer cells blocks STAT3 phosphorylation and reduces expression of STAT targets.
Targets
| STAT3 [1] (In A549 cells) |
In vitro
APTSTAT3-9R effectively inhibited phosphorylation of STAT3 but did not affect the level of AKT phosphorylation and it suppresses cell viability and proliferation of cancer cells.
In vivo
APTSTAT3-9R could effectively suppress tumor growth in the in vivo allograft and xenograft tumor models by inhibiting STAT3 phosphorylation.
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.