[CAS NO. 1253952-02-1]  Netarsudil (AR-13324) 2HCl

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PRODUCTS SPECIFICATIONS [1253952-02-1]

Store
Catalog
SLK-S8226
Brand
Selleck
CAS
1253952-02-1

DESCRIPTION [1253952-02-1]

Overview

MDLMFCD29472289
Molecular Weight526.45
Molecular FormulaC28H27N3O3.2HCl
SMILESCC1=CC(C)=C(C(OCC2=CC=C([C@H](C(NC3=CC4=C(C=NC=C4)C=C3)=O)CN)C=C2)=O)C=C1.Cl.Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.8995 mL9.4976 mL18.9952 mL
5 mM0.3799 mL1.8995 mL3.7990 mL
10 mM0.1900 mL0.9498 mL1.8995 mL
50 mM0.0380 mL0.1900 mL0.3799 mL

Description

Netarsudil (a.k.a. AR-13324) is inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension.

Targets

norepinephrine transporter (NET) [3]ROCK [1]
2 nM(Ki)