[CAS NO. 328023-11-6] Rbin-1

Name: Rbin-1
Brand: Arctom Scientific
SKU: SLK-S8376

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PRODUCTS SPECIFICATIONS [328023-11-6]

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Catalog

SLK-S8376

Brand

Selleck

CAS

328023-11-6

DESCRIPTION [328023-11-6]

Overview

MDL	MFCD02369534
Molecular Weight	256.33
Molecular Formula	C13H12N4S
SMILES	S(CC(C)=C)C=1N=C2C(C=3C(N2)=CC=CC3)=NN1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Rbin-1 (Ribozinoindole-1) is a potent chemical inhibitor of . It inhibits recombinant full-length Mdn1's ATPase activity in vitro.

Targets

Mdn1 ^[1]

In vitro

Ribozinoindoles are potent chemical inhibitors of eukaryotic ribosome assembly. Rbin-1 targets Mdn1 or cellular processes that involve this protein. It efficiently inhibit the growth of yeast cells.

References

[1] Kawashima, et al. Cell. 2016, 167:512-524.

Synonyms

5H-1,2,4-Triazino[5,6-b]indole, 3-[(2-methyl-2-propen-1-yl)thio]-

2H-1,2,4-Triazino[5,6-b]indole, 3-[(2-methyl-2-propenyl)thio]-

3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole

Ribozinoindole-1

3-[(2-Methylprop-2-en-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole