[CAS NO. 1799753-84-6]  BAY-876

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PRODUCTS SPECIFICATIONS [1799753-84-6]

Store
Catalog
SLK-S8452
Brand
Selleck
CAS
1799753-84-6

DESCRIPTION [1799753-84-6]

Overview

MDLMFCD30377201
Molecular Weight496.42
Molecular FormulaC24H16F4N6O2
SMILESO=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C#N)C=C4)N=C3C(F)(F)F)=O)=C1)N

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.0144 mL10.0721 mL20.1442 mL
5 mM0.4029 mL2.0144 mL4.0288 mL
10 mM0.2014 mL1.0072 mL2.0144 mL
50 mM0.0403 mL0.2014 mL0.4029 mL

Description

BAY-876 is a potent and selective inhibitor (IC50=0.002 μM) with a selectivity factor of >100 against GLUT2, GLUT3, and GLUT4.

Targets

GLUT1 [1]
(Cell-free assay)
0.002 μM

In vitro

BAY-876 is a highly-selective GLUT1 inhibitor with selectivity over GLUT2, 3, and 4 of 4700-, 800-, and 135-fold, respectively.