Overview
| MDL | MFCD30377201 |
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| Molecular Weight | 496.42 |
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| Molecular Formula | C24H16F4N6O2 |
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| SMILES | O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C#N)C=C4)N=C3C(F)(F)F)=O)=C1)N |
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For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg |
| 1 mM | 2.0144 mL | 10.0721 mL | 20.1442 mL |
| 5 mM | 0.4029 mL | 2.0144 mL | 4.0288 mL |
| 10 mM | 0.2014 mL | 1.0072 mL | 2.0144 mL |
| 50 mM | 0.0403 mL | 0.2014 mL | 0.4029 mL |
Description
BAY-876 is a potent and selective inhibitor (IC50=0.002 μM) with a selectivity factor of >100 against GLUT2, GLUT3, and GLUT4.
Targets
GLUT1 [1] (Cell-free assay) |
| 0.002 μM |
In vitro
BAY-876 is a highly-selective GLUT1 inhibitor with selectivity over GLUT2, 3, and 4 of 4700-, 800-, and 135-fold, respectively.