[CAS NO. 2088113-98-6] AZ31
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PRODUCTS SPECIFICATIONS [2088113-98-6]
Store
Catalog
SLK-S8556
Brand
Selleck
CAS
2088113-98-6
DESCRIPTION [2088113-98-6]
Overview
| MDL | MFCD31922712 |
|---|---|
| Molecular Weight | 420.50 |
| Molecular Formula | C24H28N4O3 |
| SMILES | COCC(C=C1)=NC=C1C2=CC3=C(C=C2)N=CC(C(N)=O)=C3N[C@@H](C)C4CCOCC4 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
AZ31 is a selective and novel inhibitor with an IC50 of <0.0012 μM. It shows excellent selectivity over closely related enzymes (>500 fold selective over DNA-PK and PI3Kα and >1000 fold selective over mTOR, PI3Kβ and PI3Kγ).
Targets
| ATM [2] |
In vitro
Antitumor effects of AZ31 + SN38 are cytostatic rather than cytotoxic.
References
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