[CAS NO. 508186-14-9] ACSS2 inhibitor
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PRODUCTS SPECIFICATIONS [508186-14-9]
Store
Catalog
SLK-S8588
Brand
Selleck
CAS
508186-14-9
DESCRIPTION [508186-14-9]
Overview
| MDL | MFCD03232237 |
|---|---|
| Molecular Weight | 410.51 |
| Molecular Formula | C20H18N4O2S2 |
| SMILES | O=C(NCCOC)NC1=CC=C2N=C(C3=CC=CS3)C(C4=CC=CS4)=NC2=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.4360 mL | 12.1800 mL | 24.3599 mL |
| 5 mM | 0.4872 mL | 2.4360 mL | 4.8720 mL |
| 10 mM | 0.2436 mL | 1.2180 mL | 2.4360 mL |
| 50 mM | - | - | - |
Description
ACSS2 inhibitor is the most potent and specific inhibitor of . ACSS2 inhibitor also inhibits the respiratory syncytial virus (RSV).
Targets
| ACSS2 [1] (Cell-free assay) |
| ~0.6 μM |
In vitro
This quinoxaline compound inhibits the ability of HepG2 cells to incorporate [14C]acetate into lipids with IC50 = 6.8 μM. The quinoxaline is also able to inhibit HepG2 utilization of [14C]acetate for histone acetylation with IC50 = 5.5 μM.
References
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