[CAS NO. 610318-03-1] Abequolixron (RGX-104)
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PRODUCTS SPECIFICATIONS [610318-03-1]
Store
Catalog
SLK-S8689
Brand
Selleck
CAS
610318-03-1
DESCRIPTION [610318-03-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 632.54 |
| Molecular Formula | C34H34Cl2F3NO3 |
| SMILES | O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1.[H]Cl |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
Abequolixron (RGX-104) is a orally bioavailable agonist that modulates innate immunity via transcriptional activation of the ApoE gene.
Targets
| LXR [1] |
In vitro
RGX-104 is an oral first-in-class LXR agonist that robustly induces ApoE expression resulting in innate-immune mediated anti-tumor activity. RGX-104 drives anti-tumor immunity by regulating the abundance and activity of myeloid derived suppressor cells (MDSC) and dendritic cells (DC).
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