[CAS NO. 2088525-31-7] Selective PI3Kδ Inhibitor 1 (compound 7n)
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PRODUCTS SPECIFICATIONS [2088525-31-7]
Store
Catalog
SLK-S8693
Brand
Selleck
CAS
2088525-31-7
DESCRIPTION [2088525-31-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 429.45 |
| Molecular Formula | C23H20FN7O |
| SMILES | CN1C(=NC(=N1)C2=CN=C(C(=N2)C3=CC(=C(C=C3)C(=O)N)F)N)C4(CC4)C5=CC=CC=C5 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.3286 mL | 11.6428 mL | 23.2856 mL |
| 5 mM | 0.4657 mL | 2.3286 mL | 4.6571 mL |
| 10 mM | 0.2329 mL | 1.1643 mL | 2.3286 mL |
| 50 mM | 0.0466 mL | 0.2329 mL | 0.4657 mL |
Description
Selective PI3Kδ Inhibitor 1 (compound 7n) is an inhibitor of with an IC50 of 0.9 nM and >1000-fold selectivity against other class I PI3K isoforms [PI3K α/γ/β=3670/1460/21300 nM].
Targets
| PI3Kδ [1] (Cell-free assay) |
| 0.9 nM |
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