[CAS NO. 38275-34-2]  PK11000

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PRODUCTS SPECIFICATIONS [38275-34-2]

Store
Catalog
SLK-S8728
Brand
Selleck
CAS
38275-34-2

DESCRIPTION [38275-34-2]

Overview

MDLMFCD00507244
Molecular Weight236.63
Molecular FormulaC6H5ClN2O4S
SMILESCS(=O)(=O)C1=NC(C(O)=O)=C(Cl)C=N1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM4.2260 mL21.1300 mL42.2601 mL
5 mM0.8452 mL4.2260 mL8.4520 mL
10 mM0.4226 mL2.1130 mL4.2260 mL
50 mM0.0845 mL0.4226 mL0.8452 mL

Description

PK11000 stabilizes the DBD of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding and effective in inducing cell death.

Targets

p53 [1]