[CAS NO. 724440-27-1] BAY-8002
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [724440-27-1]
Store
Catalog
SLK-S8747
Brand
Selleck
CAS
724440-27-1
DESCRIPTION [724440-27-1]
Overview
| MDL | MFCD05157149 |
|---|---|
| Molecular Weight | 415.85 |
| Molecular Formula | C20H14ClNO5S |
| SMILES | O=C(O)C1=CC=CC=C1NC(C2=CC(S(=O)(C3=CC=CC=C3)=O)=CC=C2Cl)=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.4047 mL | 12.0236 mL | 24.0471 mL |
| 5 mM | 0.4809 mL | 2.4047 mL | 4.8094 mL |
| 10 mM | 0.2405 mL | 1.2024 mL | 2.4047 mL |
| 50 mM | 0.0481 mL | 0.2405 mL | 0.4809 mL |
Description
BAY-8002 is a novel inhibitor and potently suppress bidirectional lactate transport. BAY-8002 significantly increases intratumor lactate levels and transiently modulates pyruvate levels.
Targets
| MCT [1] |
In vitro
BAY-8002 inhibits cellular SNARF-5 fluorescence change with an IC50 of 85 (±6) nmol/L in MCT1-expressing DLD-1 cells and displays excellent selectivity against MCT4 (IC50 > 50 μmol/L in EVSA-T cells). BAY-8002 is a dual inhibitor of MCT1 and MCT2.
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.