[CAS NO. 1919888-06-4] LY3295668
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [1919888-06-4]
Store
Catalog
SLK-S8782
Brand
Selleck
CAS
1919888-06-4
DESCRIPTION [1919888-06-4]
Overview
| MDL | MFCD31807628 |
|---|---|
| Molecular Weight | 489.95 |
| Molecular Formula | C24H26ClF2N5O2 |
| SMILES | O=C([C@@]1(CC2=NC(NC3=NNC(C)=C3)=CC=C2F)C[C@@H](C)N(CC4=CC=CC(Cl)=C4F)CC1)O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.0410 mL | 10.2051 mL | 20.4102 mL |
| 5 mM | 0.4082 mL | 2.0410 mL | 4.0820 mL |
| 10 mM | 0.2041 mL | 1.0205 mL | 2.0410 mL |
| 50 mM | 0.0408 mL | 0.2041 mL | 0.4082 mL |
Description
LY3295668 (AK-01) is a potent, orally active and specific inhibitor of with Ki of 0.8 nM and 1038 nM for AURKA and AURKB, respectively.
Targets
| AURKA [1] (Cell-free assay) |
| 0.8 nM(Ki) |
In vitro
LY3295668, an AURKA inhibitor with over 1,000-fold selectivity versus AURKB, is distinguished by minimal toxicity to bone marrow cells at concentrations active against RB1 cancer cells.
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.