[CAS NO. 2244904-70-7]  BAY-293

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PRODUCTS SPECIFICATIONS [2244904-70-7]

Store
Catalog
SLK-S8826
Brand
Selleck
CAS
2244904-70-7

DESCRIPTION [2244904-70-7]

Overview

MDLMFCD31813755
Molecular Weight448.58
Molecular FormulaC25H28N4O2S
SMILESN(C1=NC(=NC2C=C(C(=CC=21)OC)OC)C)[C@@H](C1SC=C(C2C=CC=CC=2CNC)C=1)C

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2293 mL11.1463 mL22.2926 mL
5 mM0.4459 mL2.2293 mL4.4585 mL
10 mM0.2229 mL1.1146 mL2.2293 mL
50 mM0.0446 mL0.2229 mL0.4459 mL

Description

BAY-293 selectively inhibits the interaction with an IC50 of 21 nM.

Targets

K-ras [1]
21 nM

In vitro

BAY-293 (compound 23) selectively inhibits the KRAS–SOS1 interaction with an IC50 of 21 nM.