[CAS NO. 1801530-11-9]  Imidazole ketone erastin (PUN30119)

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PRODUCTS SPECIFICATIONS [1801530-11-9]

Store
Catalog
SLK-S8877
Brand
Selleck
CAS
1801530-11-9

DESCRIPTION [1801530-11-9]

Overview

MDLMFCD31813799
Molecular Weight655.14
Molecular FormulaC35H35ClN6O5
SMILESO=C1N(C2=CC(C(CN3C=CN=C3)=O)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.5264 mL7.6320 mL15.2639 mL
5 mM0.3053 mL1.5264 mL3.0528 mL
10 mM0.1526 mL0.7632 mL1.5264 mL
50 mM0.0305 mL0.1526 mL0.3053 mL

Description

Imidazole ketone erastin (PUN30119, IKE) is a potent, selective, and metabolically stable inhibitor and inducer of .

Targets

Ferroptosis [1]system xc– [1]

In vitro

Imidazole ketone erastin (IKE) is an erastin analog with nanomolar potency, high metabolic stability, and intermediate water solubility. Its treatment potently reduces DLBCL cell number.