Overview
| MDL | - |
|---|
| Molecular Weight | 268.28 |
|---|
| Molecular Formula | C9H14F2N2O3S |
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| SMILES | - |
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For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg |
| 1 mM | 3.7274 mL | 18.6372 mL | 37.2745 mL |
| 5 mM | 0.7455 mL | 3.7274 mL | 7.4549 mL |
| 10 mM | 0.3727 mL | 1.8637 mL | 3.7274 mL |
| 50 mM | 0.0745 mL | 0.3727 mL | 0.7455 mL |
Description
MK-8719 is a selective and potent small molecule inhibitor of the enzyme with ki of 7.9nM for hOGA.
Targets
hOGA [1] (Cell-free assay) |
| 7.9nM(Ki) |
In vitro
In vitro, MK-8719 is a potent inhibitor of the human OGA enzyme with comparable activity against the corresponding enzymes from mouse, rat, and dog.