[CAS NO. 2664214-60-0]  BI-4020

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PRODUCTS SPECIFICATIONS [2664214-60-0]

Store
Catalog
SLK-S8921
Brand
Selleck
CAS
2664214-60-0

DESCRIPTION [2664214-60-0]

Overview

MDLMFCD32263045
Molecular Weight542.68
Molecular FormulaC30H38N8O2
SMILESC(C=1C=C2N3/C(/NC2=CC1)=N/C(=O)C=4C=C(C5=C(OCCC[C@@H](C)C3)N(C)N=C5)N=C(C)C4)N6CCN(C)CC6

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

BI-4020 is an orally active, non-covalent inhibitor with IC50 of 0.6 nM and 0.2 nM for EGFR as biomarker potency and anti-proliferation potency in BaF3 cells, respectively.

Targets

EGFRdel19 T790M C797S [1]
(anti-proliferation potency)
EGFRdel19 T790M C797S [1]
(biomarker potency)
0.2 nM0.6 nM