[CAS NO. 2252403-56-6] Sotorasib (AMG510) racemate

Name: Sotorasib (AMG510) racemate
Brand: Arctom Scientific
SKU: SLK-S8955

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PRODUCTS SPECIFICATIONS [2252403-56-6]

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Catalog

SLK-S8955

Brand

Selleck

CAS

2252403-56-6

DESCRIPTION [2252403-56-6]

Overview

MDL	-
Molecular Weight	560.59
Molecular Formula	C30H30F2N6O3
SMILES	O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.7838 mL	8.9192 mL	17.8383 mL
5 mM	0.3568 mL	1.7838 mL	3.5677 mL
10 mM	0.1784 mL	0.8919 mL	1.7838 mL
50 mM	0.0357 mL	0.1784 mL	0.3568 mL

Description

Sotorasib (AMG510) racemate is a racemic of AMG-510 which is a potent covalent inhibitor with potential antineoplastic activity.

Targets

KRAS G12Cv ^[1]

References

[1] Tatu Pantsar. Sci Rep . 2020 Jul 20;10(1):11992.

Synonyms

Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-

6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one