[CAS NO. 55916-51-3]  Polyphyllin VI

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PRODUCTS SPECIFICATIONS [55916-51-3]

Store
Catalog
SLK-S9302
Brand
Selleck
CAS
55916-51-3

DESCRIPTION [55916-51-3]

Overview

MDL-
Molecular Weight738.90
Molecular FormulaC39H62O13
SMILESO[C@@]12[C@]3(C)[C@@](C[C@@]1(O[C@@]4([C@H]2C)CC[C@@H](C)CO4)[H])([C@]5([C@](CC3)([C@]6(C)C(=CC5)C[C@@H](O[C@H]7[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](O)[C@H](O)[C@@H](CO)O7)CC6)[H])[H])[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Polyphyllin VI derived from Paris polyphylla possess anti-cancer activities.

In vitro

Polyphyllin VI (PPVI) induces activation of the NLRP3 inflammasome and exerts anti-proliferative effect via the induction of the ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer (NSCLC).[1]


Synonyms

β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
(3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
Pennogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside
Polygonatoside B3
Polyphyllin VI
Paris VI
Saponin Tb
17-Hydroxyparis V
Paris saponin VI
Pennogenin-3-O-α-L-rhamnopyranosyl(1→2)-β-D-glucoside