[CAS NO. 1034895-42-5] 9-ing-41
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PRODUCTS SPECIFICATIONS [1034895-42-5]
Store
Catalog
SLK-S9602
Brand
Selleck
CAS
1034895-42-5
DESCRIPTION [1034895-42-5]
Overview
| MDL | MFCD16495778 |
|---|---|
| Molecular Weight | 404.35 |
| Molecular Formula | C22H13FN2O5 |
| SMILES | O=C(C(C1=COC2=CC=C(F)C=C12)=C3C4=CN(C)C5=C4C=C6C(OCO6)=C5)NC3=O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.4731 mL | 12.3655 mL | 24.7310 mL |
| 5 mM | 0.4946 mL | 2.4731 mL | 4.9462 mL |
| 10 mM | 0.2473 mL | 1.2366 mL | 2.4731 mL |
| 50 mM | 0.0495 mL | 0.2473 mL | 0.4946 mL |
Description
9-ING-41 is a potent inhibitor of with antitumor activity. 9-ING-41 induces and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK3β.
Targets
| GSK-3 [1] |
In vitro
9-ING-41, a clinically relevant small molecule GSK-3β inhibitor with broad spectrum pre-clinical antitumor activity, suppresses the growth of neuroblastoma cells. 9-ING-41 induces apoptosis and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK3β.
References
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