[CAS NO. 2457232-14-1] G6PDi-1
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PRODUCTS SPECIFICATIONS [2457232-14-1]
Store
Catalog
SLK-S9617
Brand
Selleck
CAS
2457232-14-1
DESCRIPTION [2457232-14-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 284.34 |
| Molecular Formula | C14H12N4OS |
| SMILES | N#CC=1SC=C(C1)NC2=NC=C3C(=O)CCCCC3=N2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.5169 mL | 17.5846 mL | 35.1692 mL |
| 5 mM | 0.7034 mL | 3.5169 mL | 7.0338 mL |
| 10 mM | 0.3517 mL | 1.7585 mL | 3.5169 mL |
| 50 mM | 0.0703 mL | 0.3517 mL | 0.7034 mL |
Description
G6PDi-1 is an effective inhibitor of . G6PDi-1 depletes and decreases inflammatory cytokine production.
In vitro
G6PDi-1 effectively inhibits G6PD. Across a range of cultured cells, G6PDi-1 depletes NADPH most strongly in lymphocytes. In T cells but not macrophages, G6PDi-1 markedly decreases inflammatory cytokine production. In neutrophils, it suppresses respiratory burst.
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